NECAB1 抗体 (N-Term)
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Quick Overview for NECAB1 抗体 (N-Term) (ABIN7879629)
抗原
See all NECAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- N-terminal EF-hand calcium binding protein 1 Antibody / NECAB1
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human NECAB1 protein was used as the immunogen for the N-terminal EF-hand calcium binding protein 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the N-terminal EF-hand calcium binding protein 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the N-terminal EF-hand calcium binding protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))
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别名
- N-terminal EF-hand calcium binding protein 1
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背景
- Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
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UniProt
- Q8N987
抗原
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