GNRHR 抗体 (N-Term)
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北京 101111
Quick Overview for GNRHR 抗体 (N-Term) (ABIN7879607)
抗原
See all GNRHR 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- N-Term
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原理
- GnRH-Receptor Antibody / LHCG Receptor (azide and preservative free)
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序列
- MANSASPEQN QHCSAINNSI PLMQGNLPY
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纯化方法
- Protein A/G affinity
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免疫原
- amino acids MANSASPEQNQHCSAINNSIPLMQGNLPY from the N-terminal of human GnRH receptor was used as the immunogen for the GnRH-Receptor antibody.
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亚型
- IgG1, kappa
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anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (AA 201-328) antibody
GNRHR 适用: 人, 大鼠 WB, ELISA, IHC (p), IHC (fro), ICC, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (AA 3-13), (Extracellular) antibodyGNRHR 适用: 大鼠 WB, IF, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (Internal Region) antibodyVerified GNRHR 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) (N-Term) antibodyGNRHR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) antibodyGNRHR 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GnRH-Receptor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the GnRH-Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
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别名
- GnRH-Receptor
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背景
- Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.
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UniProt
- P30968
抗原
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