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CD83 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects CD83 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7879583
发货至: 中国
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Quick Overview for CD83 抗体 (N-Term) (ABIN7879583)

抗原

See all CD83 抗体
CD83

适用

  • 105
  • 62
  • 25
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1

宿主

  • 71
  • 47
  • 11
  • 3
  • 2
小鼠

克隆类型

  • 70
  • 57
  • 3
单克隆

标记

  • 58
  • 13
  • 11
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD83 antibody is un-conjugated

应用范围

  • 70
  • 58
  • 23
  • 20
  • 11
  • 10
  • 8
  • 6
  • 4
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

1H4b
  • 抗原表位

    • 16
    • 12
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    CD83 Antibody (azide and preservative free)

    纯化方法

    Protein G affinity

    免疫原

    Prokaryotic recombinant protein corresponding to 124 amino acids of the external N-terminus of the CD83 molecule was used as the immunogen for the CD83 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CD83 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CD83 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD83

    别名

    CD83

    背景

    CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature Dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting Dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anti-cancer vaccine. CD83-IgG1(Fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like Lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting Dendritic cell interactions with monocytes and CD8+ T cells.

    UniProt

    Q01151
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