Recombinant ACTH 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Recombinant ACTH 抗体 (N-Term) (ABIN7879557)
抗原
See all ACTH 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
原理
- ACTH Antibody / Synacthen
-
纯化方法
- Protein A/G affinity
-
免疫原
- The N-terminal portion of the human protein was used as the immunogen for the ACTH antibody.
-
亚型
- IgG, kappa
-
-
anti-Adrenocorticotropic hormone (ACTH) antibody
ACTH 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A4H4 unconjugated
anti-Adrenocorticotropic hormone (ACTH) antibodyACTH 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A9C6 unconjugated
anti-Adrenocorticotropic hormone (ACTH) (AA 1-39) antibodyACTH 适用: 人, 大鼠 ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Adrenocorticotropic hormone (ACTH) (AA 18-39) antibodyACTH 适用: 大鼠 ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Adrenocorticotropic hormone (ACTH) antibodyACTH 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenocorticotropic hormone (ACTH) (pSer168) antibodyACTH 适用: 人 DB 宿主: 兔 Polyclonal RB16586 unconjugated
-
-
应用备注
- Optimal dilution of the ACTH antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- ACTH (Adrenocorticotropic hormone (ACTH))
-
别名
- ACTH
-
背景
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to Synacthen (aa1-24 of ACTH), does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
-
UniProt
- P01189
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
抗原
-
