ZFYVE28 抗体 (full length)
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北京 101111
Quick Overview for ZFYVE28 抗体 (full length) (ABIN7879378)
抗原
See all ZFYVE28 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- ZFYVE28 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant full-length human protein was used as the immunogen for this ZFYVE28 antibody.
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亚型
- IgG2a, kappa
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anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) antibody
ZFYVE28 适用: 人 IHC 宿主: 小鼠 Monoclonal LST2-2426 unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 1-887) antibodyZFYVE28 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 604-633), (C-Term) antibodyZFYVE28 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB27835 unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 131-180) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (N-Term) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 604-633), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 611-642), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ZFYVE28 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the ZFYVE28 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ZFYVE28 (Zinc Finger, FYVE Domain Containing 28 (ZFYVE28))
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别名
- ZFYVE28
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背景
- ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs.
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UniProt
- Q9HCC9
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途径
- EGFR Signaling Pathway
抗原
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