ZNF408 抗体 (full length)
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Quick Overview for ZNF408 抗体 (full length) (ABIN7879354)
抗原
See all ZNF408 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- ZNF408 Antibody / PRDM17
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human ZNF408 protein was used as the immunogen for the ZNF408 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the ZNF408 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ZNF408 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ZNF408 (Zinc Finger Protein 408 (ZNF408))
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别名
- ZNF408
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背景
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
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UniProt
- Q9H9D4
抗原
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