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ZBTB46 抗体 (full length)

The 小鼠 单克隆 anti-ZBTB46 antibody is suitable to detect ZBTB46 in samples from 人. It has been validated for WB, IF, FACS 和 IHC (p).
产品编号 ABIN7879350
发货至: 中国
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Quick Overview for ZBTB46 抗体 (full length) (ABIN7879350)

抗原

See all ZBTB46 (ZNF340) 抗体
ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

适用

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  • 1
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宿主

  • 38
  • 5
小鼠

克隆类型

  • 40
  • 3
单克隆

标记

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  • 4
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  • 1
  • 1
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This ZBTB46 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PCRP-ZBTB46-2B8
  • 抗原表位

    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    ZBTB46 Antibody / BTBD4 / ZNF340

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human Zinc finger and BTB domain-containing protein 46 protein was used as the immunogen for the ZBTB46 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the ZBTB46 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ZBTB46 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

    别名

    ZBTB46

    背景

    BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

    UniProt

    Q86UZ6
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