ZBTB46 抗体 (full length)
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北京 101111
Quick Overview for ZBTB46 抗体 (full length) (ABIN7879350)
抗原
See all ZBTB46 (ZNF340) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- ZBTB46 Antibody / BTBD4 / ZNF340
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human Zinc finger and BTB domain-containing protein 46 protein was used as the immunogen for the ZBTB46 antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the ZBTB46 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ZBTB46 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
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别名
- ZBTB46
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背景
- BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
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UniProt
- Q86UZ6
抗原
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