Transgelin 抗体 (full length)
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北京 101111
Quick Overview for Transgelin 抗体 (full length) (ABIN7879183)
抗原
See all Transgelin (TAGLN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Transgelin Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human protein was used as the immunogen for the Transgelin antibody.
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亚型
- IgG1, kappa
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anti-Transgelin (TAGLN) (C-Term) antibody
Verified TAGLN 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyTAGLN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyKO Validated TAGLN 适用: 人 WB, IHC (p), IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Transgelin (TAGLN) (AA 19-112) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Transgelin (TAGLN) (AA 2-201) antibodyTAGLN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 24-51), (N-Term) antibodyTAGLN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19881 unconjugated
anti-Transgelin (TAGLN) antibodyTAGLN 适用: 人, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the Transgelin antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Transgelin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Transgelin (TAGLN)
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别名
- Transgelin
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背景
- This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.
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UniProt
- Q01995
抗原
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