Recombinant Transgelin 抗体 (full length)
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Quick Overview for Recombinant Transgelin 抗体 (full length) (ABIN7879181)
抗原
See all Transgelin (TAGLN) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Recombinant Transgelin Antibody / SM22 alpha (azide and preservative free)
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序列
- TAGLN
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human Transgelin (TAGLN) protein was used as the immunogen for the recombinant Transgelin antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the recombinant Transgelin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Transgelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Transgelin (TAGLN)
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别名
- Transgelin
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背景
- This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.
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UniProt
- Q01995
抗原
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