TGFB2 抗体 (full length)
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Quick Overview for TGFB2 抗体 (full length) (ABIN7879179)
抗原
See all TGFB2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- TGF beta 2 Antibody / TGFB2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the TGF beta 2 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the TGF beta 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the TGF beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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别名
- TGF beta 2
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背景
- Transforming growth factor Bs (TGFbs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFa. It is now realized that TGFbs mediate many cell-cell interactions that occur during embryonic development. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.
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UniProt
- P10600
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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