Recombinant TOP1MT 抗体 (full length)
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北京 101111
Quick Overview for Recombinant TOP1MT 抗体 (full length) (ABIN7879164)
抗原
See all TOP1MT 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Recombinant TOP1MT Antibody
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纯化方法
- Protein A affinity chromatography
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免疫原
- Recombinant full-length human protein was used as the immunogen for the recombinant TOP1MT antibody.
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亚型
- IgG, kappa
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应用备注
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Optimal dilution of the recombinant TOP1MT antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant TOP1MT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
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别名
- TOP1MT
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背景
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
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UniProt
- Q969P6
抗原
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