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TOP1MT 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects TOP1MT in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7879157
发货至: 中国
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Quick Overview for TOP1MT 抗体 (full length) (ABIN7879157)

抗原

See all TOP1MT 抗体
TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

适用

  • 62
  • 8
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 38
  • 28
小鼠

克隆类型

  • 44
  • 22
单克隆

标记

  • 33
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TOP1MT antibody is un-conjugated

应用范围

  • 37
  • 20
  • 19
  • 14
  • 12
  • 9
  • 7
  • 6
  • 4
  • 4
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

TOP1MT-568
  • 抗原表位

    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    TOP1MT Antibody / Topoisomerase I mitochondrial (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant full-length human protein was used as the immunogen for the TOP1MT antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the TOP1MT antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TOP1MT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

    别名

    TOP1MT

    背景

    DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

    UniProt

    Q969P6
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