TOP1MT 抗体 (full length)
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北京 101111
Quick Overview for TOP1MT 抗体 (full length) (ABIN7879157)
抗原
See all TOP1MT 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- TOP1MT Antibody / Topoisomerase I mitochondrial (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human protein was used as the immunogen for the TOP1MT antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the TOP1MT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the TOP1MT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
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别名
- TOP1MT
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背景
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
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UniProt
- Q969P6
抗原
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