Th-POK (full length) 抗体
This 小鼠 单克隆 antibody specifically detects Th-POK in FACS, IF 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN7879139
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Th-POK (full length) 抗体 (ABIN7879139)
抗原
Th-POK
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
质量等级
Carrier-free
克隆位点
PCRP-ZBTB7B-1B6
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抗原表位
- full length
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原理
- Th-Pok Antibody / ZBTB7B (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human Zinc finger and BTB domain-containing protein 7B protein was used as the immunogen for the Th-Pok antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Th-Pok antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Th-Pok antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Th-POK
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背景
- TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.
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UniProt
- O15156
抗原
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