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TARBP2 抗体 (full length)

The 小鼠 单克隆 anti-TARBP2 antibody is suitable to detect TARBP2 in samples from 人. It has been validated for WB, IF 和 FACS.
产品编号 ABIN7879128
发货至: 中国
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Room 801-803
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Quick Overview for TARBP2 抗体 (full length) (ABIN7879128)

抗原

See all TARBP2 抗体
TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TARBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-TARBP2-1E5
  • 抗原表位

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    full length

    原理

    TARBP2 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human TARBP2 protein was used as the immunogen for the TARBP2 antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the TARBP2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TARBP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

    别名

    TARBP2

    背景

    TRBP2, also known as TARBP2 (trans-activation-responsive (HIV-1) RNA binding protein 2), TRBP1 or TRBP, is a nuclear protein that contains three DRBM (double-stranded RNA-binding) domains. TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. The third DRBM motif in the C-terminus of human TRBP2 can interact with and inhibit PKR activity, thereby increasing HIV-1 long terminal repeat (LTR) expression. In addition, TRBP2 functions as a component of a Dicer-containing complex and associates with the catalytic subunit of the RNA-induced silencing complex (RISC), namely eIF2C2. TRBP2 is essential for Dicer stability and the proper assembly of RISC. This suggests that TRBP2, in association with Dicer, plays an important role in the processing of miRNAs (microRNAs).

    UniProt

    Q15633

    途径

    Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
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