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TAL1 抗体 (full length)

The 小鼠 单克隆 anti-TAL1 antibody is suitable to detect TAL1 in samples from 人. It has been validated for ELISA.
产品编号 ABIN7879113
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TAL1 抗体 (full length) (ABIN7879113)

抗原

See all TAL1 抗体
TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TAL1 antibody is un-conjugated

应用范围

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ELISA

质量等级

Carrier-free

克隆位点

TAL1-2707
  • 抗原表位

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    full length

    原理

    TAL1 Antibody / T-cell acute lymphocytic leukemia protein 1 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human full-length TAL1 protein was used as the immunogen for the TAL1 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the TAL1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TAL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

    别名

    TAL1

    背景

    Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.

    UniProt

    P17542

    途径

    Stem Cell Maintenance
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