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SPIC 抗体 (full length)

The 小鼠 单克隆 anti-SPIC antibody is suitable to detect SPIC in samples from 人. It has been validated for IF 和 FACS.
产品编号 ABIN7879074
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SPIC 抗体 (full length) (ABIN7879074)

抗原

See all SPIC 抗体
SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

适用

  • 30
  • 15
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1

宿主

  • 35
  • 3
小鼠

克隆类型

  • 35
  • 3
单克隆

标记

  • 23
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPIC antibody is un-conjugated

应用范围

  • 19
  • 15
  • 5
  • 5
  • 3
  • 1
Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-SPIC-2C5
  • 抗原表位

    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    SPIC Antibody / Transcription factor Spi-C

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human Transcription factor Spi-C protein was used as the immunogen for the SPIC antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the SPIC antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SPIC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

    别名

    SPIC

    背景

    The Ets transcription factor family is comprised of DNA-binding proteins that influence lymphoid development and activity and bind the consensus DNA site GGA(A/T) through a unique winged helix-turn-helix motif known as the Ets domain. Spi-B and Spi-C (also known as SPIC) are closely related Ets family members which share a conserved divergent sequence within the Ets domain that enables their binding to non-canonical AGAA sites. Spi-C is a 248 amino acid protein that localizes to the nucleus and, like other Ets family members, binds DNA as a monomer and plays a role in transcriptional regulation. Addi- tionally, Spi-C is thought to control the development of red pulp macrophages, thereby contributing to iron homeostasis and red blood cell recycling. Human Spi-C shares 65 % amino acid identity with its mouse counterpart, suggesting a conserved role between species.

    UniProt

    Q8N5J4
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