Spastin 抗体 (full length)
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北京 101111
Quick Overview for Spastin 抗体 (full length) (ABIN7879069)
抗原
See all Spastin (SPAST) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Spastin Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full length human Spastin protein was used as the immunogen for the Spastin antibody.
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亚型
- IgG2a, kappa
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anti-Spastin (SPAST) (AA 200-304) antibody
SPAST 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Spastin (SPAST) (AA 200-305) antibodySPAST 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Spastin (SPAST) (AA 551-616) antibodySPAST 适用: 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Spastin (SPAST) antibodySPAST 适用: 小鼠, 大鼠, 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spastin (SPAST) (AA 200-304) antibodySPAST 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Spastin (SPAST) antibodySPAST 适用: 小鼠, 大鼠, 人 WB, ELISA, IF, IHC 宿主: 小鼠 Monoclonal Sp 3G11-1 unconjugated
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应用备注
- Optimal dilution of the Spastin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Spastin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Spastin (SPAST)
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别名
- Spastin
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背景
- The AAA protein family members share an ATPase domain and have roles in various cellular processes including intracellular motility, membrane trafficking, proteolysis, protein folding and organelle biogenesis. Spastin, a member of the AAA protein family, is a 616 amino acid protein and is involved in the function or assembly of nuclear protein complexes. The Spastin protein is expressed ubiquitously and localizes to the nucleus and the cytoplasm, where it may also be involved in microtubule dynamics. Mutations in the Spastin gene (SPAST, SPG4) cause the most common form of spastic paraplegia 4, an autosomal dominant form of hereditary spastic paraplegia (HSP). HSPs comprise a group of inherited neurological disorders characterized by spastic lower extremity weakness due to a length-dependent, retrograde axonopathy of corticospinal motor neurons. SPAST-specific mutations account for approximately 40 % of all autosomal dominant HSPs.
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途径
- Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
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