CD43 抗体 (full length)
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北京 101111
Quick Overview for CD43 抗体 (full length) (ABIN7879031)
抗原
See all CD43 (SPN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD43 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CD43 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CD43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD43 (SPN) (Sialophorin (SPN))
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别名
- CD43
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背景
- It recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. 70-90 % of T-cell lymphomas and from 22-37 % of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
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UniProt
- P16150
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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