CD43 抗体 (full length)
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北京 101111
Quick Overview for CD43 抗体 (full length) (ABIN7879030)
抗原
See all CD43 (SPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- CD43 Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CD43 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD43 (SPN) (Sialophorin (SPN))
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别名
- CD43
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背景
- CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]
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UniProt
- P16150
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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