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NUMB 抗体 (pSer276)

This anti-NUMB antibody (ABIN744428) is a Rabbit Polyclonal antibody detecting NUMB in WB, ELISA, IF (cc), IF (p), ICC, IHC (fro). Suitable for Mouse.
产品编号 ABIN744428
发货至: 中国

Quick Overview for NUMB 抗体 (pSer276) (ABIN744428)

抗原

See all NUMB 抗体
NUMB (Numb Homolog (NUMB))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This NUMB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer276

    特异性

    This phosphorylation site is homologous to that of Ser276 in Mouse and Ser275 in Rat.

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Numb around the phosphorylation site of Ser276

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Mah, Soloff, Hedrick, Mariani: "Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway." in: Stem cell reports, Vol. 5, Issue 5, pp. 866-80, (2015) (PubMed).

  • 抗原

    NUMB (Numb Homolog (NUMB))

    别名

    Numb

    背景

    Synonyms: S171, C14orf41, c14_5527, Protein numb homolog, h-Numb, Protein S171, NUMB

    Background: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

    基因ID

    8650

    UniProt

    P49757

    途径

    Cell-Cell Junction Organization
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