Recombinant RORC 抗体 (full length)
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北京 101111
Quick Overview for Recombinant RORC 抗体 (full length) (ABIN7878935)
抗原
See all RORC 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Recombinant ROR gamma Antibody / RORC
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human ROR gamma T protein was used as the immunogen for the recombinant ROR gamma antibody.
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亚型
- IgG, kappa
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anti-RAR-Related Orphan Receptor C (RORC) (AA 212-461) antibody
RORC 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 200-212) antibodyVerified RORC 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 110-159) antibodyRORC 适用: 人, Cow, 马, 豚鼠, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 1-50) antibodyRORC 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 4G419 unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 412-517) antibodyRORC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (N-Term) antibodyRORC 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠, 犬, 兔 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (Middle Region) antibodyRORC 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) antibodyRORC 适用: 人 ELISA 宿主: 小鼠 Monoclonal RORC-2942 unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 1-518) antibodyRORC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (Modulating Domain) antibodyRORC 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the recombinant ROR gamma antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant ROR gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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别名
- ROR gamma
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背景
- Retina-associated orphan receptors (RORs) contains three subtypes: RORAlpha, RORBeta, and RORGamma. They are widely distributed in body tissues, and most of them can directly enter the nucleus to regulate the transcription of target genes, thus showing different tissue specificity and participating in different physiological processes. In particular, RORAlpha and RORGamma play an important role in mediating Th17 cell differentiation. RORGamma can be divided into RORGamma1 and RORGamma2 (RORGamma T), which show different tissue specificity. ROR Gamma (T) is expressed only in lymphoid compartment cells, i.e., CD4+CD8+ double positive thymocytes, peripheral Th17 cells, and lymphoid tissue inducer (LTi) cells of lymphoid organs. At present, RORGamma T is considered as a new target for drug development against autoimmune diseases, especially psoriasis. In recent years, RORGamma T small molecule inhibitors have become a hot research field in academia and even international pharmaceutical companies, with great development potential.
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UniProt
- P51449
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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