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QKI 抗体 (full length)

The 小鼠 单克隆 anti-QKI antibody (Clone PCRP-QKI-2F10) (ABIN7878886) specifically detects QKI in WB, IF, ELISA 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7878886
发货至: 中国
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Quick Overview for QKI 抗体 (full length) (ABIN7878886)

抗原

See all QKI 抗体
QKI (Protein Quaking (QKI))

适用

  • 79
  • 30
  • 15
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2

宿主

  • 43
  • 37
  • 1
小鼠

克隆类型

  • 52
  • 29
单克隆

标记

  • 45
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This QKI antibody is un-conjugated

应用范围

  • 69
  • 49
  • 30
  • 27
  • 27
  • 10
  • 7
  • 6
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-QKI-2F10
  • 抗原表位

    • 27
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    QKI Antibody / Protein Quaking (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the QKI antibody.

    亚型

    IgG2c
  • 应用备注

    Optimal dilution of the QKI antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the QKI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    QKI (Protein Quaking (QKI))

    别名

    QKI

    背景

    QKI, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, QKI functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5. Additionally, QKI regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. QKI may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases QKI mRNA-binding affinity. Defects or deletions in the gene encoding QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of QKI exist due to alternative splicing events.

    UniProt

    Q96PU8
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