LMYC 抗体 (full length)
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Quick Overview for LMYC 抗体 (full length) (ABIN7878880)
抗原
See all LMYC (MYCL) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- L-Myc Antibody / MYCL1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human MYCL protein was used as the immunogen for the L-Myc antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the L-Myc antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the L-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LMYC (MYCL) (Protein L-Myc (MYCL))
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别名
- L-Myc
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背景
- Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.
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UniProt
- P12524
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途径
- Warburg Effect
抗原
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