PCGF3 抗体 (full length)
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Quick Overview for PCGF3 抗体 (full length) (ABIN7878825)
抗原
See all PCGF3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- PCGF3 Antibody / Polycomb group RING finger protein 3 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the PCGF3 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the PCGF3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the PCGF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))
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别名
- PCGF3
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背景
- Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.
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UniProt
- Q3KNV8
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途径
- Chromatin Binding
抗原
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