POGZ 抗体 (full length)
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北京 101111
Quick Overview for POGZ 抗体 (full length) (ABIN7878822)
抗原
See all POGZ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- POGZ Antibody / Pogo transposable element with ZNF domain
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human Pogo transposable element with ZNF domain protein was used as the immunogen for the POGZ antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the POGZ antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the POGZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- POGZ (Pogo Transposable Element with ZNF Domain (POGZ))
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别名
- POGZ
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背景
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
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UniProt
- Q7Z3K3
抗原
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