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Peroxiredoxin 4 抗体 (full length)

The 小鼠 单克隆 anti-Peroxiredoxin 4 antibody (Clone CPTC-PRDX4-2) (ABIN7878790) specifically detects Peroxiredoxin 4 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7878790
发货至: 中国
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Quick Overview for Peroxiredoxin 4 抗体 (full length) (ABIN7878790)

抗原

See all Peroxiredoxin 4 (PRDX4) 抗体
Peroxiredoxin 4 (PRDX4)

适用

  • 79
  • 40
  • 28
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 61
  • 24
  • 1
小鼠

克隆类型

  • 48
  • 38
单克隆

标记

  • 50
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Peroxiredoxin 4 antibody is un-conjugated

应用范围

  • 57
  • 34
  • 29
  • 9
  • 8
  • 7
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA

克隆位点

CPTC-PRDX4-2
  • 抗原表位

    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    Peroxiredoxin 4 Antibody / PRDX4

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human PRDX4 protein was used as the immunogen for the Peroxiredoxin 4 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Peroxiredoxin 4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the Peroxiredoxin 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Peroxiredoxin 4 (PRDX4)

    别名

    Peroxiredoxin 4

    背景

    The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX IV gene is expressed in many tissues. It exists as a precursor protein, which is only detected in testis, and aprocessed secreted form. PRX IV is highly expressed in lung cancer and is necessary for the promotion of lung cancer in vitro. Studies have demonstrated that PRX IV positive expression is significantly correlated with recurrences and shorter disease-free survival in patients with early-stage lung squamous cell carcinoma, and therefore can be used as a prognostic marker in lung squamous cell carcinoma.

    UniProt

    Q13162
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