NME2 抗体 (full length)
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Quick Overview for NME2 抗体 (full length) (ABIN7878750)
抗原
See all NME2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- NDKB Antibody / Nucleoside diphosphate kinase B / NME2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the NDKB antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the NDKB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the NDKB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NME2 (Nucleoside diphosphate kinase B (NME2))
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别名
- NDKB
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背景
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
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UniProt
- P22392
抗原
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