NRF1 抗体 (full length)
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北京 101111
Quick Overview for NRF1 抗体 (full length) (ABIN7878725)
抗原
See all NRF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- NRF1 Antibody / Nuclear Respiratory Factor 1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant full-length human protein was used as the immunogen for this NRF1 antibody.
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亚型
- IgG1, kappa
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anti-Nuclear Respiratory Factor 1 (NRF1) (AA 201-285) antibody
NRF1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) antibodyNRF1 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 272-288), (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) antibodyNRF1 适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 51-180) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 360-409) antibodyNRF1 适用: 人, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 猴, 小鸡, 犬, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 201-285) antibodyNRF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 429-478) antibodyNRF1 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 1-300) antibodyNRF1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NRF1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the NRF1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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别名
- NRF1
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背景
- The NF-E2 DNA binding protein is composed of two subunits, p45 and MafK, and it regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (MAREs). A family of NF-E2 related proteins, which are collectively known as the Cap 'n' collar (CNC) family and include Nrf1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. They do so by heterodimerizing with Jun family members (c-Jun, JunB and JunD) to activate gene expression, specifically the detoxifying enzyme, NQO1. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1. Nrf3 is highly expressed in placenta, B cells and monocytes.
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UniProt
- Q16656
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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