NMI 抗体 (full length)
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北京 101111
Quick Overview for NMI 抗体 (full length) (ABIN7878699)
抗原
See all NMI 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- N-Myc Interactor Antibody / NMI / N-myc and STAT interactor (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human N-Myc Interactor protein was used as the immunogen for the N-Myc Interactor antibody.
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亚型
- IgG2b
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anti-N-Myc (And STAT) Interactor (NMI) (AA 1-100) antibody
NMI 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 9D8 unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-307) antibodyNMI 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-100) antibodyNMI 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 9E8 unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 62-202) antibodyNMI 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) antibodyKD Validated NMI 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2560 unconjugated Recombinant Antibody
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-307) antibodyNMI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (C-Term) antibodyNMI 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (C-Term) antibodyNMI 适用: 人 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) antibodyNMI 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 2-307) antibodyNMI 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the N-Myc Interactor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the N-Myc Interactor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NMI (N-Myc (And STAT) Interactor (NMI))
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别名
- N-Myc Interactor
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背景
- Nmi (for N-Myc interactor) is an interferon inducible protein that associates with multiple transcription factors, including c-Myc, n-Myc, Max, and c-Fos, which contain bHLH-ZIP, bHLH, or Zip domains. Nmi is ubiquitously expressed at low levels throughout various fetal and adult tissues and at higher levels in myeloid leukemias and cell lines overexpressing c-Myc. In addition to binding Myc proteins, Nmi also associates with the Stat family of transcription factors, where it enhances Stat-dependent transcription. Although Nmi lacks an intrinsic DNA binding or activation domain, Nmi enhances the transcriptional activity of the Stat proteins, in response to cytokine stimulation, by recruiting the Stat1 and Stat5 transcriptional coactivators, CREB-binding protein (CBP) and p300. In vitro studies indicate that Nmi, expressed in conjunction with CBP, enhances the transcriptional responsiveness of Stat5 to IL-2 stimulation five-fold over CBP alone by increasing the affinity of Stat proteins for CBP/p300.
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UniProt
- Q13287
抗原
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