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MEF2B 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects MEF2B in WB, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878686
发货至: 中国
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Quick Overview for MEF2B 抗体 (full length) (ABIN7878686)

抗原

See all MEF2B 抗体
MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

适用

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宿主

  • 33
  • 5
小鼠

克隆类型

  • 34
  • 4
单克隆

标记

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This MEF2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-MEF2B-2F9
  • 抗原表位

    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    full length

    原理

    MEF2B Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human MEF2B protein was used as the immunogen for the MEF2B antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the MEF2B antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MEF2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

    别名

    MEF2B

    背景

    The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

    UniProt

    Q02080
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