MPZ 抗体 (full length)
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北京 101111
Quick Overview for MPZ 抗体 (full length) (ABIN7878681)
抗原
See all MPZ 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- MPZ Antibody / Myelin Protein Zero (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human MPZ protein was used as the immunogen for the MPZ antibody.
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亚型
- IgG2a, kappa
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anti-Myelin Protein Zero (MPZ) (AA 175-248) antibody
MPZ 适用: 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (C-Term) antibodyMPZ 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 186-215), (C-Term) antibodyMPZ 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21459 unconjugated
anti-Myelin Protein Zero (MPZ) (AA 193-223), (C-Term) antibodyMPZ 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 1-258) antibodyMPZ 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) antibodyMPZ 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 30-248) antibodyMPZ 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (Internal Region) antibodyVerified MPZ 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Myelin Protein Zero (MPZ) (AA 1-258) antibodyMPZ 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Myelin Protein Zero (MPZ) (AA 30-156) antibodyMPZ 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MPZ antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the MPZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MPZ (Myelin Protein Zero (MPZ))
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别名
- MPZ
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背景
- Zero, also known as myelin protein zero (MPZ) is a Type 1 integral membrane glycoprotein that mediates adhesion of spiraling wraps of the myelin sheath in order to ensure stable synaptic transmission. Zero protein encompasses approximately 50 % of total protein in the sheath scaffolding in contribution to structural integrity of peripheral myelin. Zero guides the compact myelin wrapping process through glycine zipper packing interface-dependent dimer and tetramer formation. Mutations (e.g. G134R) can abrogate multimer formation, cause demyelinating neuropathies, and are known to contribute to conditions that include Charcot-Marie-Tooth disease. Zero cytoplasmic domain undergoes serine and tyrosine phosphorylation, which appears to be prevalent during peak nerve myelination. Zero transcript is moderate in brain, abundant in thymus and most abundant in white matter of the CNS.
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UniProt
- P25189
抗原
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