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MUC16 抗体 (full length)

The 小鼠 单克隆 anti-MUC16 antibody is suitable to detect MUC16 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7878642
发货至: 中国
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Quick Overview for MUC16 抗体 (full length) (ABIN7878642)

抗原

See all MUC16 (CA125) 抗体
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

适用

  • 161
  • 8
  • 3

宿主

  • 88
  • 77
  • 4
  • 2
  • 1
小鼠

克隆类型

  • 126
  • 40
  • 4
单克隆

标记

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  • 10
  • 6
  • 6
  • 4
  • 4
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  • 4
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
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This MUC16 antibody is un-conjugated

应用范围

  • 74
  • 66
  • 41
  • 20
  • 18
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  • 16
  • 11
  • 4
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MUC16-1860
  • 抗原表位

    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    MUC16 Antibody / CA125

    纯化方法

    Protein G affinity chromatography

    免疫原

    Full length native MUC16 protein purified from human ovarian carcinoma was used as the immunogen for this MUC16 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Mucin 16 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Mucin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    别名

    MUC16

    背景

    The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

    UniProt

    Q8WXI7
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