MTF1 抗体 (full length)
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北京 101111
Quick Overview for MTF1 抗体 (full length) (ABIN7878612)
抗原
See all MTF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- MTF1 Antibody / Metal regulatory transcription factor 1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant full-length human protein was used as the immunogen for the MTF1 antibody.
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亚型
- IgG1, kappa
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anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 2-139) antibody
MTF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 41-140) antibodyMTF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) antibodyMTF1 适用: 人 IHC 宿主: 小鼠 Monoclonal MTF1-2649 unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 101-200) antibodyMTF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Metal-Regulatory Transcription Factor 1 (MTF1) (AA 562-611) antibodyMTF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MTF1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the MTF1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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别名
- MTF1
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背景
- The metal-responsive element (MRE)-binding transcription factor (MTF-1) stimulates the expression of metallothioneins in response to the exposure of cells to heavy metals. MTF-1 contains six zinc fingers in the DNA binding domain. The phosphorylation of MTF-1 in response to metal exposure appears to play a significant role in the ability of MTF-1 to activate metallothionein transcription. In addition to its role in metallothionein activation, MTF-1 is involved in a post-transcription regulatory complex for ribosomal protein S25. MTF-1, La and p53 inhibit the nuclear export of S25 mRNA in response to nutrient depravation. Furthermore, MTF-1 acts as a chromatin insulator on integrated transgenes in cultured cells to insulate active loci against chromatin silencing.
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UniProt
- Q14872
抗原
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