电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MED7 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects MED7 in ELISA, FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7878596
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MED7 抗体 (full length) (ABIN7878596)

抗原

See all MED7 抗体
MED7 (Mediator Complex Subunit 7 (MED7))

适用

  • 52
  • 12
  • 8
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2

宿主

  • 44
  • 8
小鼠

克隆类型

  • 46
  • 6
单克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED7 antibody is un-conjugated

应用范围

  • 44
  • 22
  • 13
  • 13
  • 12
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

质量等级

Carrier-free

克隆位点

PCRP-MED7-1B8
  • 抗原表位

    • 15
    • 12
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    MED7 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the MED7 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the MED7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the MED7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MED7 (Mediator Complex Subunit 7 (MED7))

    别名

    MED7

    背景

    MED7 (Mediator of RNA polymerase II transcription subunit 7), also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, MED7 functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5. Additionally, MED7 regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. MED7 may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases MED7 mRNA-binding affinity. Defects or deletions in the gene encoding MED7 are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of MED7 exist due to alternative splicing events.

    UniProt

    O43513

    途径

    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
You are here: