MED22 抗体 (full length)
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北京 101111
Quick Overview for MED22 抗体 (full length) (ABIN7878594)
抗原
See all MED22 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- MED22 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human protein was used as the immunogen for the MED22 antibody.
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亚型
- IgG2c
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应用备注
- Optimal dilution of the MED22 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the MED22 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MED22 (Mediator Complex Subunit 22 (MED22))
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别名
- MED22
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背景
- Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.
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UniProt
- Q15528
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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