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MED21 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects MED21 in WB, ELISA, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878590
发货至: 中国
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Quick Overview for MED21 抗体 (full length) (ABIN7878590)

抗原

See all MED21 抗体
MED21 (Mediator Complex Subunit 21 (MED21))

适用

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宿主

  • 19
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小鼠

克隆类型

  • 20
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单克隆

标记

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This MED21 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-MED21-4B5
  • 抗原表位

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    full length

    原理

    MED21 Antibody / SRB7 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human MED21 protein was used as the immunogen for the MED21 antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the MED21 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the MED21 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MED21 (Mediator Complex Subunit 21 (MED21))

    别名

    MED21

    背景

    In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors. Med6 and Med7, as well as other components of SMCC, associate with co-activator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation. Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity

    UniProt

    Q13503

    途径

    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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