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MLX 抗体 (full length)

The 小鼠 单克隆 anti-MLX antibody (Clone PCRP-MLX-1G8) (ABIN7878589) specifically detects MLX in WB, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7878589
发货至: 中国
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Quick Overview for MLX 抗体 (full length) (ABIN7878589)

抗原

See all MLX 抗体
MLX (MAX-Like Protein X (MLX))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MLX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-MLX-1G8
  • 抗原表位

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    full length

    原理

    MLX Antibody / Max-like protein X

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human MLX protein was used as the immunogen for the MLX antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the MLX antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MLX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MLX (MAX-Like Protein X (MLX))

    别名

    MLX

    背景

    Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad1, Mad3, Mad4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad1, Mad4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.

    UniProt

    Q9UH92
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