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MXI1 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects MXI1 in WB, IF 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7878587
发货至: 中国
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Quick Overview for MXI1 抗体 (full length) (ABIN7878587)

抗原

See all MXI1 抗体
MXI1 (MAX Interactor 1 (MXI1))

适用

  • 39
  • 28
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  • 5
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  • 4
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  • 2
  • 2
  • 2
  • 2
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  • 1

宿主

  • 37
  • 7
  • 2
小鼠

克隆类型

  • 39
  • 7
单克隆

标记

  • 30
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  • 1
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This MXI1 antibody is un-conjugated

应用范围

  • 30
  • 19
  • 6
  • 5
  • 3
  • 2
  • 1
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  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-MXI1-1A3
  • 抗原表位

    • 8
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    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    full length

    原理

    MXI1 Antibody / Max-interacting protein 1 / BHLHC11

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human MXI1 protein was used as the immunogen for the MXI1 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the MXI1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MXI1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MXI1 (MAX Interactor 1 (MXI1))

    别名

    MXI1

    背景

    It is now well established that Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, is an obligate heterodimeric partner for Myc and can also form heterodimers with at least four related proteins designated Mad 1, Mxi1 (also designated Mad 2), Mad 3 and Mad 4. Like Mad 1 and Mxi1, association of Mad 3 and Mad 4 with Max results in transcriptional repression. Both Myc and the Mad proteins have short half-lives and their synthesis is tightly regulated, while Max expression is constitutive and relatively stable. Two related mammalian cDNAs have been identified and shown to encode Mad- binding proteins. Both possess sequence homology with the yeast transcription repressor Sin3 including four conserved paired amphipathic helix (PAH) domains. mSin3A and mSin3B specifically interact with the Mad proteins via their second paired amphipathic helix domain (PAH2). It has been suggested that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.

    UniProt

    P50539

    途径

    Maintenance of Protein Location
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