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Recombinant L1CAM 抗体 (full length)

This 兔 单克隆 antibody specifically detects L1CAM in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878530
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant L1CAM 抗体 (full length) (ABIN7878530)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 87
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  • 1
单克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

L1CAM-9146R
  • 抗原表位

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    full length

    原理

    Recombinant NCAM-L1 Antibody / CD171 / L1CAM (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human L1CAM protein was used as the immunogen for the recombinant NCAM-L1 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant NCAM-L1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant NCAM-L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    NCAM-L1

    背景

    L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

    UniProt

    P32004

    途径

    Synaptic Membrane
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