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Recombinant L1CAM 抗体 (full length)

The 小鼠 单克隆 anti-L1CAM antibody (Clone rL1CAM-9163) (ABIN7878529) specifically detects L1CAM in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7878529
发货至: 中国
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Quick Overview for Recombinant L1CAM 抗体 (full length) (ABIN7878529)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RL1CAM-9163
  • 抗原表位

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    full length

    原理

    Recombinant L1CAM Antibody / CD171 / NCAM-L1

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human L1CAM protein was used as the immunogen for the recombinant L1CAM antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the recombinant L1CAM antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    L1CAM

    背景

    L1 (L1 cell adhesion molecule) also known as CAML1, CD171, and HSAS is an adhesion molecule which plays an important role in the nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.

    UniProt

    P32004

    途径

    Synaptic Membrane
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