Keratin 6B 抗体 (full length)
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北京 101111
Quick Overview for Keratin 6B 抗体 (full length) (ABIN7878504)
抗原
See all Keratin 6B (KRT6B) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Cytokeratin 6B Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant full-length human KRT6B protein was used as the immunogen for the Cytokeratin 6B antibody.
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亚型
- IgG2a, kappa
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anti-Keratin 6B (KRT6B) (AA 1-564) antibody
KRT6B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Keratin 6B (KRT6B) (AA 207-236) antibodyKRT6B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33708 unconjugated
anti-Keratin 6B (KRT6B) (AA 1-564) antibodyKRT6B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Keratin 6B (KRT6B) (AA 1-280) antibodyKRT6B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Cytokeratin 6B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cytokeratin 6B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Keratin 6B (KRT6B)
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别名
- Cytokeratin 6B
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背景
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
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UniProt
- P04259
抗原
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