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HDAC3 抗体 (full length)

The 小鼠 单克隆 anti-HDAC3 antibody is suitable to detect HDAC3 in samples from 人. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7878375
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC3 抗体 (full length) (ABIN7878375)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HDAC3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-HDAC3-3C9
  • 抗原表位

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    full length

    原理

    HDAC3 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human HDAC3 protein was used as the immunogen for the HDAC3 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the HDAC3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the HDAC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3

    背景

    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.

    UniProt

    O15379

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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