GTF2IRD2 抗体 (full length)
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Quick Overview for GTF2IRD2 抗体 (full length) (ABIN7878330)
抗原
See all GTF2IRD2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- GTF2IRD2 alpha Antibody / GTF2IRD2 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human General transcription factor II-I repeat domain-containing protein 2A protein was used as the immunogen for the GTF2IRD2 alpha antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the GTF2IRD2 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the GTF2IRD2 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
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别名
- GTF2IRD2 alpha
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背景
- The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (also called GTF2IRD2 alpha and GTF2IRD2A) and GTF2IRD2B. Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
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UniProt
- Q86UP8
抗原
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