GCLM 抗体 (full length)
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北京 101111
Quick Overview for GCLM 抗体 (full length) (ABIN7878299)
抗原
See all GCLM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- GLCLR Antibody / GCLM
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human GLCLR protein was used as the immunogen for the GCLM antibody.
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亚型
- IgG2a, kappa
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anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 246-274), (C-Term) antibody
GCLM 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22980 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 40-251) antibodyGCLM 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274), (Regulatory Subunit) antibodyGCLM 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) antibodyKD Validated GCLM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5535 unconjugated Recombinant Antibody
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 245-274), (C-Term) antibodyGCLM 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (N-Term) antibodyGCLM 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 182-231) antibodyGCLM 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) (AA 1-274) antibodyGCLM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GLCLR antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GLCLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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别名
- GLCLR
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背景
- G-glutamylcysteine synthetase (g-GCS) is the rate limiting enzyme for glutathione (L-g-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. g-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic antioxidants, heat shock, oxidants and cytokines. The human g-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human g-GCS gene encoding the regulatory subunit maps to chromosome 1p22.1. The two subunits of g-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
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UniProt
- P48507
抗原
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