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Gastrin 抗体 (full length)

The 小鼠 单克隆 anti-Gastrin antibody is suitable to detect Gastrin in samples from 人. It has been validated for ELISA.
产品编号 ABIN7878258
发货至: 中国
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Quick Overview for Gastrin 抗体 (full length) (ABIN7878258)

抗原

See all Gastrin (GAST) 抗体
Gastrin (GAST)

适用

  • 104
  • 36
  • 34
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  • 1

宿主

  • 76
  • 42
  • 2
  • 1
小鼠

克隆类型

  • 71
  • 50
单克隆

标记

  • 63
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  • 1
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This Gastrin antibody is un-conjugated

应用范围

  • 57
  • 48
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  • 1
ELISA

质量等级

Carrier-free

克隆位点

GAST-2632
  • 抗原表位

    • 15
    • 9
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
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    full length

    原理

    Gastrin Antibody (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant full-length human GAST protein was used as the immunogen for this Gastrin antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Gastrin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Gastrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Gastrin (GAST)

    别名

    Gastrin

    背景

    Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

    UniProt

    P01350
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