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Recombinant FLI1 抗体 (full length)

This 兔 单克隆 antibody specifically detects FLI1 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878257
发货至: 中国
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Quick Overview for Recombinant FLI1 抗体 (full length) (ABIN7878257)

抗原

See all FLI1 抗体
FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

抗体类型

Recombinant Antibody

适用

  • 115
  • 48
  • 22
  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4

宿主

  • 80
  • 35
  • 2

克隆类型

  • 65
  • 52
单克隆

标记

  • 77
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FLI1 antibody is un-conjugated

应用范围

  • 92
  • 48
  • 33
  • 29
  • 19
  • 11
  • 10
  • 8
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

FLI1-4371R
  • 抗原表位

    • 22
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    FLI1 Antibody

    纯化方法

    Protein A affinity

    免疫原

    Recombinant full-length human FLI1 protein was used as the immunogen for the FLI1 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the FLI1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FLI1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

    别名

    FLI1

    背景

    Recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing s Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

    UniProt

    Q01543
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