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Ezrin 抗体 (full length)

The 小鼠 单克隆 anti-Ezrin antibody (Clone SPM244) (ABIN7878214) specifically detects Ezrin in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7878214
发货至: 中国
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Quick Overview for Ezrin 抗体 (full length) (ABIN7878214)

抗原

See all Ezrin (EZR) 抗体
Ezrin (EZR)

适用

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宿主

  • 146
  • 22
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小鼠

克隆类型

  • 124
  • 45
单克隆

标记

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This Ezrin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM244
  • 抗原表位

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    full length

    原理

    Ezrin Antibody / EZR

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human full-length protein was used as the immunogen for this Ezrin antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Ezrin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Ezrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Ezrin (EZR)

    别名

    Ezrin

    背景

    Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.

    UniProt

    P15311

    途径

    Maintenance of Protein Location
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