Ezrin 抗体 (full length)
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北京 101111
Quick Overview for Ezrin 抗体 (full length) (ABIN7878213)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Ezrin Antibody / EZR (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human full-length protein was used as the immunogen for this Ezrin antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Ezrin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Ezrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Ezrin (EZR)
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别名
- Ezrin
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背景
- Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
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