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CKM 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects CKM in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878038
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CKM 抗体 (full length) (ABIN7878038)

抗原

See all CKM 抗体
CKM (Creatine Kinase, Muscle (CKM))

适用

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宿主

  • 111
  • 33
  • 15
  • 1
  • 1
小鼠

克隆类型

  • 124
  • 36
单克隆

标记

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  • 1
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  • 1
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  • 1
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This CKM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CKMM-3341
  • 抗原表位

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    • 8
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    • 1
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    full length

    原理

    Creatine Kinase M Antibody / CKM

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant full-length CKM protein was used as the immunogen for the Creatine Kinase M antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the Creatine Kinase M antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Creatine Kinase M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CKM (Creatine Kinase, Muscle (CKM))

    别名

    Creatine Kinase M

    背景

    T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

    UniProt

    P06732
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