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Recombinant CD8 alpha 抗体 (full length)

The 兔 单克隆 anti-CD8 alpha antibody (Clone CD8-7793R) (ABIN7877959) specifically detects CD8 alpha in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7877959
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD8 alpha 抗体 (full length) (ABIN7877959)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CD8-7793R
  • 抗原表位

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    full length

    原理

    CD8A Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant human full-length CD8a protein was used as the immunogen for the CD8A antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the CD8A antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the CD8A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8A

    背景

    This mAb is specific for the 32 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

    UniProt

    P01732

    途径

    TCR Signaling
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